Test for functional integrity of methylmalonyl CoA mutase and methionine synthase using propionate or methyltetrahydrofolate incorporation into macromolecules by cultured cells

This skipping, internal tandem duplications, and information is mandatory to assess the sequence variants in select oncogenes (see validity of the test. [...] - Frozen tissue minimally 30 mg of tissue on This test may be ordered for patients with the dry ice following tumour types: - Fresh tissue on RNA later minimally 30 mg of tissue Sarcomas Cholangiocarcinomas If no fresh/frozen tissue is available: Brain tumours - FFPE blocks are NOT accepted Rare solid tumours - Scrolls or unstained slides from Formalin- Certain hematological malignancies. [...] Test Interpretation If results obtained do not match other clinical Only variants with a recognized or predictive or laboratory findings, or if you have novel diagnostic, prognostic or therapeutic clinical relevant information, please contact the significance are reported (Tier I and II; PMID: laboratory as soon as possible for updated 27993330). [...] This test cannot definitively determine whether a variant is present in the Results may be compromised if the germline or restricted to the tumour. [...] A negative result does not fully rule out the presence of an alteration and may be due to the limitations of this assay (i.e.