For the most hard-hit countries, such as the US, Italy and Spain, there are greater percentages of older population who are facing much higher risks of hospitalization and fatality due to changes of immune system and the impact of preexisting health conditions over time.1 Studies have found that COVID-19 was an emergent disease of ageing.2 The effects of population ageing on the outcomes of COVID-. [...] Studies have emphasized the importance of incorporating the demographic information in curbing the spread of the epidemic.3 An important recent study by the Imperial College COVID-19 Response Team explored the impacts of public health interventions in 11 European countries.4 Here we focus on individual cities where the policy steps are more homogeneous and can be well-described in the model we pre. [...] Scenario design for interventions and the timing of policy action Applying the SEIR-HQD model, we designed two sets of scenarios to explore: 1) the age-specific effects of policy interventions and 2) the effectiveness of policy action at different time points since the diagnosis of the first case. [...] The age-specific effects of different interventions on the outcomes of COVID-19 Figure 3 presents the temporal evolution of the number of individuals in each wellness/illness category (“status”) over a year period in the four cities simulated per million residents of initial susceptible population with no intervention. [...] The four colors of shadows represent four interventions and the widths of the shadows represent the duration of each intervention.
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- United States of America