E-CIGARETTES BACKGROUND - Nicotine salt formulas in the most recent generation

For the purposes of this resource we refer to the entire category as “e-cigarettes.” E-cigarette use among young people has skyrocketed in recent years and remains at epidemic levels: about one in five high school students used e-cigarettes in 2020, many of whom were not smokers in the first place. [...] The nicotine salt formulas allow for much higher levels and efficient delivery > The most popular, JUUL, is a pre-filled pod of nicotine with less irritation compared system containing nicotine salts that emerged in to earlier generations of e-cigarettes 2015 and quickly established itself as a leading — prompting questions about the use, e-cigarette product. [...] 15 Higher nicotine e-cigarettes have driven the surge in e-cigarette sales in recent > “Copycat” products, such as Suorin Drop, myblu, years, with those containing at least 4% and Vuse Alto, followed JUUL’s blueprint of high- nicotine comprising nearly three-quarters tech design and high nicotine delivery through of the e-cigarette market in 2018.9 Unlike nicotine salt e-liquid formulations. [...] The use of illnesses related to vaping nicotine salts also lowers the pH of e-liquids, which allows higher concentrations have raised questions about of nicotine to be delivered with less irritation.23 For example, the maker of JUUL both the long- and short-term claims the product has a nicotine content effects of vaping. [...] like traditional cigarettes, and that it delivers the nicotine up to 2.7 times faster than other > In addition to the rate of nicotine delivery, e-cigarettes.24 the nicotine content of products like JUUL > In the U.