Pathology of callosal damage in ALS_ An ex-vivo, 7T diffusion tensor MRI study - main

Coronal view of the same hemisphere showing the location of the VOI at the level of the body of the corpus callosum. [...] The FA of the genu and body of the FA of the genu (FAg CTL, black circles) and the body of the callosum (FAb CTL black the callosum was expressed as a ratio to the FA of the splenium for the squares) lie close to the values for the splenium. [...] PMI exhibited a strong correlation with the patient (# 3) had mild spongiosis that was noted in the body of the FA of the splenium of the corpus callosum of the group of 6 subjects corpus callosum. [...] PMI was not demyelination in the genu and body of the corpus callosum in several correlated with the FA of the genu or body of the callosum, although in ALS patients. [...] Varying degrees of callosum in ALS patients compared to the control; however, in ALS beading and a corkscrew appearance of the axons in the body of the patients reactive astrogliosis scores were also higher in other segments corpus callosum were present both in ALS patients and in the control of the callosum in ALS compared to controls (Fig.