Surveillance, case investigation and contact tracing for mpox: interim guidance, 27 November 2024

Table of Contents

• Key points 1
• Changes from earlier version 2
• Introduction 2
• Monkeypox virus in animals 3
• Surveillance case definitions 4
• MPXV reinfection – Case definitions 5
• Definition of mpox death for surveillance purposes 7
• Surveillance 7
• Mpox community-based surveillance 9
• Indications for mpox testing 9
• Reporting 10
• Case investigation 11
• Investigating exposure to an infected animal 12
• Contact tracing 13
• Definition of a contact 13
• Contact identification and notification 14
• Contact monitoring 14
• Measures for mpox contacts 15
• Management of symptomatic contacts who become cases 15
• Monitoring exposed health workers 15
• Travel-related contact tracing 16
• Monitoring and evaluation of contact tracing quality 17
• Wastewater and environmental surveillance for mpox 17
• Data collection and sharing 18
• Methods 18
• Plans for updating 18
• Acknowledgments 19
• References 20