Global Priority List of Antibiotic-Resistant Bacteria to Guide Research, Discovery, and Development
28 February 2017
SELECTION OF CRITERIA FOR PRIORITIZATION The following ten criteria were selected by the coordinating group of experts on the basis of their experience and previous prioritization exercises, reflecting the principles of MCDA (completeness, non-redundancy, non-overlap and preference independence): all-cause mortality, healthcare and community burden, prevalence of resistance, 10-year trend of resis. [...] There were no changes in the ranking of the list of pathogens after taking into account the background of the experts or their country of origin. [...] The results of the MCDA ranking and the sensitivity analysis were compared during the meeting; all differences between the lists were discussed and adjudicated. [...] The experts agreed on grouping the pathogens according to the species and the type of resistance and then stratifying the results in three priority tiers: critical, high and medium. [...] REMARKS The evaluation of the evidence-based data underlines the essential role of infection control measures in reducing the spread of antibiotic-resistant bacteria and the large heterogeneity among the WHO regions in terms of implementation.