Herpes simplex virus: global infection prevalence and incidence estimates, 2016

We then applied age and sex, the countries contributing the search strategy, data extraction and these proportions to HSV type 1 inci- data and the inclusion criteria applied is synthesis, and definitions of general dence only in those 15–49 years of age available in the data repository.23 populations are in the data repository.23 to estimate the numbers with oral and In comparison with the 2012 e [...] Before pooling, we adjusted to the National Health and Nutrition repository.23 the prevalence values for the sensitiv- Evaluation Survey 2015–2016, the larg- ity and specificity of the tests used to est, national population-based survey Prevalence of infection detect HSV in different studies (data in the USA.29 We calculated the total Our estimates for 2016 found that a repository).23 Smoothed pre [...] The regional regional pooled prevalence values and respectively, bringing the totals to 4850.1 pooled prevalence values and model fits model fits are available in the data million and 836.0 million, respectively for HSV type 2 infection is available in repository.23 Note that the number of (data repository).23 the data repository.23 people with oral and genital HSV type 1 The global prevalence of [...] The number of people with genital HSV type 1 infections in 2016 genital HSV type 1 was highest in the (data repository).23 Incidence of infection Region of the Americas, followed by the Taken together,. [...] There was a general 596.0 million–655.7 million people, UI: 21.0 million–29.5 million) people trend of increasing numbers of people 16.0–17.6% of the world’s population 15–49 years of age became infected infected with both oral and genital HSV 15–49 years of age, had genital HSV with HSV type 2 in 2016, an incidence type 1 infection by age, mirroring the type 1 or HSV type 2 or both, based on of 0