Nitrosamines

Nitrosamines (or more formally N-Nitrosamines) are organic compounds of the chemical structure R2N−N=O, where R is usually an alkyl group. They feature a nitroso group (NO+) bonded to a deprotonated amine. Most nitrosamines are carcinogenic.

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NBER: National Bureau of Economic Research · 31 May 2024 English

We use data from the Population Assessment of Tobacco Use and Health (PATH), a longitudinal data set including self-reported and biomarker measures of tobacco use, to examine the effects of …

which belongs to a family of tobacco- specific nitrosamines (TSNA). As suggested by their name, TSNAs are biology, and carcinogenicity of tobacco-specific N-nitrosamines.” Chemical Research in Toxicology 11 (6):559–603


EU: European Union · 2 May 2024 English

products can give rise to the formation of nitrosamines, some of which have been found to be carcinogenic balance between the risk of the formation of nitrosamines through the presence of nitrites in meat products added to foods were reduced to keep the level of nitrosamines potentially formed due to that use as low as prevalence of botulism and the formation of nitrosamines in processed meat products. (29) In light relates in particular to the increased risk of nitrosamines formation. Contrary to EFSA’s opinion of 2017


EU: European Union · 23 April 2024 English

oj 7/27 Table 3 Requirements on amines and nitrosamines for rubbers Parameter Restriction Sum of Primary secondary amines (2) MTC tap = 250 μg/l Sum of N-nitrosamines (3) MTC tap = N.D. (LOD = 0,1 μg/l) (1) Method pyrrolidine (CAS 930-55-2) Table 4 Requirements on nitrosamines for final materials other than rubbers made chlorinated test water Parameter Restriction Sum of N-nitrosamines (1) MTC tap = N.D. (LOD = 0,1 μg/l) (1) sum


IRSST: Institut de recherche Robert-Sauvé en santé et en sécurité du travail · 17 April 2024 English

Page 1 of 54 Laboratory Services Offered by the IRSST April 2024 POLICY ON THE USE OF THE LABORATORY SERVICES OFFERED BY THE IRSST Cost The cost of the sampling …

500 mg Nitrosamines Package only N-Nitrosodiethylamine 2210 Florisil tube, 500 mg Nitrosamines Package 500 mg Nitrosamines Package only N-Nitrosodipropylamine 2210 Florisil tube, 500 mg Nitrosamines Package 500 mg Nitrosamines Package only N-Nitrosomorpholine 2210 Florisil tube, 500 mg Nitrosamines Package 500 mg Nitrosamines Package only N-Nitrosopyrrolidine 2210 Florisil tube, 500 mg Nitrosamines Package PACKAGES (cont.) Inorganic Acids - volatiles 8 Nitrosamines by GC-NPD 7 amines by LC-MS Chromium VI Cassette


ASH: Action on Smoking and Health · 4 April 2024 English

For all ethnic groups, 54.0% of the white population attempting to quit reported success, compared with 55.0% of the Asian or Asian British and 53.9% of the black or black …

of nicotine and carcinogenic tobacco specific nitrosamines (TSNAs). As a result, they often have varying Smokeless Tobacco and Some Tobacco-specific N- Nitrosamines. IARC Monographs on the evaluation of Carcinogenic unprotonated nicotine, tobacco-specific N'-Nitrosamines, and flavor compounds. Food Chem Toxicol. Food unionised nicotine and tobacco-specific N- nitrosamines Tob Control, 2011. 13 Sinha et al., Prevalence


AUDA-NEPAD: African Union Development Agency-NEPAD · 7 February 2024 English

In addition, the checklist will facilitate the demonstration of the eligibility of the medicinal product for the EMP TC procedure. [...] The Integrated Overview and Conclusions should clearly define the …

journals. PAGE 31 N-Nitrosamine impurities N-Nitrosamines are a class of substances of concern to international pharmaceutical industry. This is because many nitrosamines are highly potent mutagenic agents that have expected that a risk assessment for the presence of nitrosamines should be conducted and completed prior to submission manufacturing process for the FPP). N-Nitrosamines N-Nitrosamines are a class of substances of concern pharmaceutical industry. This is because many nitrosamines are highly potent mutagenic agents that have


EU: European Union · 12 January 2024 English

and the risk of the formation of carcinogenic nitrosamines through the presence of nitrites in meat products provisions further minimise the risk posed by nitrosamines which is its primary concern. Denmark emphasises


Brookings Institution · 11 January 2024 English

On March 2, 2023, the authors convened a group of experts from academia, industry, government, and nonprofits to explore technology options for increasing the resilience in the supply of generic …

impurities that may appear during production, with nitrosamines as a prominent example. Another key failure


Eli Lilly and Company Foundation · 2024 English

excipients and potential impurities such as nitrosamines, and similar regulations and standards (and


EU: European Union · 31 December 2023 English

The main focus of the REF-10 enforcement project was the integrated control of chemicals in products (substances, mixtures and articles) within different legislation such as the REACH Regulation, POP Regulation, …

Forum REF – 10 Project report 16 Toys Nitrosamines CMR Thiazolines Migration EN 71:3 TCP 13 and some balloons had an excessive amount of nitrosamines. In three toys consisting of soft plastic there if non-compliant (CAS No.): ⃝ ⃝ Nitrosamines and nitrosatable substances Please specify 1117-81-7 3 Fragrances 10 0 0% Nitrosamines…. 13 2 15% Sum of: 5336-53-816 /643014-99-717


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