E - Commission on Narcotic Drugs - Summary of assessments, findings and recommendations

Actual abuse and/or evidence of likelihood of abuse Studies in experimental animals demonstrate that dipentylone has an abuse potential similar to that of methamphetamine, which is listed under Schedule II of the Convention on Psychotropic Substances of 1971, and cocaine, which is listed under Schedule I of the Convention on Narcotic Drugs of 1961. [...] Similarity to known substances and effects on the central nervous system The mechanism of action of 2-fluorodeschloroketamine is uncertain, but it has effects similar to those of N- methyl-D-aspartate receptor antagonists such as phencyclidine, which are controlled under Schedule II of the Convention on Psychotropic Substances of 1971. [...] Rationale and recommendation The mechanism of action and ill effects of bromazolam are similar to those of other benzodiazepines, such as alprazolam and diazepam, that are listed under Schedule IV of the Convention on Psychotropic Substances of 1971. [...] Similarity to known substances and effects on the central nervous system Carisoprodol is an analogue of meprobamate and has effects similar to those of other central nervous system depressants such as meprobamate, pentobarbital, diazepam and chlordiazepoxide that are listed under schedules III and IV of the Convention on Psychotropic Substances of 1971. [...] Actual abuse and/or evidence of likelihood of abuse In animal models indicative of abuse liability, the effects of carisoprodol were similar to those of pentobarbital, chlordiazepoxide and meprobamate in a dose-dependent manner.