Assessment of the potential health hazard posed by environmental exposure to

87 Assessment of the potential health hazard posed by environmental exposure to cytotoxic pharmaceuticals in New Zealand 5 LIST OF TABLES TABLE 1 CYTOTOXIC DRUGS DISPENSED IN NEW ZEALAND IN 2021 AND 2022 ....... [...] 35 Accessed 9 February 2023 Assessment of the potential health hazard posed by environmental exposure to cytotoxic pharmaceuticals in New Zealand 22 Table 5 Summary of studies assessing presence of the 21 target cytotoxic drugs in municipal wastewater Matrix Pharmaceutical Analyte Countries not found in Countries detected in Max conc. [...] Assessment of the potential health hazard posed by environmental exposure to cytotoxic pharmaceuticals in New Zealand 24 Table 6 Summary of studies assessing presence of 21 target cytotoxic drugs in hospital wastewater Pharmaceutical Analyte Countries not found in Countries detected in Max conc. [...] Of the ten studies that assessed the presence of fluorouracil in municipal wastewater, it was only detected in two, with a maximum concentration of 3.5 ng/L in untreated wastewater and < LOQ in treated wastewater (Table 14). [...] Studies Assessment of the potential health hazard posed by environmental exposure to cytotoxic pharmaceuticals in New Zealand 53 assessing the presence of these drugs in wastewater effluent, as discussed above, will be able to guide the investigation in this area, as wastewater effluents are likely to be one of the most significant sources of cytotoxic drugs to these environments.