Effectiveness of magnetic resonance imaging (MRI) screening for women at high risk of breast cancer

The sensitivity of MRI was Effectiveness of magnetic resonance imaging (MRI) screening for women at high risk of breast cancer iv reported in five of the 10 included studies. [...] The rigour of development was found to be low, specificity of MRI ranged from 81% to 97.2% because the inclusion and exclusion criteria, the and that of mammography ranged from 93% to external review process, and the process for 96.8%. [...] For MRI, the sensitivity was 100%, in Appendix 1. Table 1 describes the sensitivity which was higher than the sensitivity of the and specificity of MRI and mammography. [...] MRI led to the detection of seven cases of breast The reliability of MRI screening for women at cancer that were not detected using the other risk of breast cancer was studied in 23 women methods, the authors deemed MRI to be cost- with a proven or suspected BRCA1/2 mutation.21 effective at about €6,000 per MRI-detected Women were included if they had a proven breast cancer.12 BRCA1/2 mutation, a [...] Only five of the 10 studies measured the was the factor that most affected the cost- sensitivity and specificity of the screening tests.