Health Technology Assessment
Authors
- Pages
- 86
- Published in
- Canada
Table of Contents
- Abbreviations 7
- Executive Summary 8
- Background and Policy Context 8
- Clinical Evidence 8
- Limitations 9
- Conclusions and Implications for Decision- or Policy-Making 9
- Introduction and Rationale 9
- Background and Rationale 9
- Clinical Review Methods 15
- Project Scope 15
- Objective 15
- Policy Question 15
- Research Question 15
- Review Conduct 16
- Eligibility Criteria 16
- Literature Search Methods 19
- Study Selection Process 19
- Data Extraction 20
- Risk of Bias Assessments 21
- Data Analysis and Synthesis 21
- Results of Clinical Evaluation 22
- Selection of Primary Studies 22
- Study and Patient Characteristics 23
- Summary of Risk of Bias Assessment 28
- Data Analysis and Synthesis 30
- Discussion 38
- Summary of the Evidence 38
- Interpretation of Clinical Results From the Systematic Review 39
- Additional Considerations 41
- Strengths and Limitations of the Systematic Review 44
- Conclusions and Implications for Decision- or Policy-Making 45
- References 47
- Appendix 1: Literature Search Strategy 51
- Appendix 2: List of Included Studies 63
- Appendix 3: List of Excluded Studies 65
- Appendix 4: Summary of Study Characteristics 76
- Appendix 5: Risk of Bias Assessment 81