Authors
Guillaume Baudry, Ouarda Pereira, Kévin Duarte, João Pedro Ferreira, Gianluigi Savarese, Adeline Welter, Philippe Tangre, Zohra Lamiral, Nelly Agrinier, Nicolas Girerd
- Bibliographic Reference
- Guillaume Baudry, Ouarda Pereira, Kévin Duarte, João Pedro Ferreira, Gianluigi Savarese, et al.. Risk of readmission and death after hospitalization for worsening heart failure: Role of post-discharge follow-up visits in a real-world study from the Grand Est Region of France. European Journal of Heart Failure, 2023, ⟨10.1002/ejhf.3103⟩. ⟨hal-04329446⟩
- DOI
- https://doi.org/10.1002/ejhf.3103
- HAL Collection
- ['Université de Lorraine', 'DCAC - Défaillance Cardiovasculaire Aiguë et Chronique', 'Pôle scientifique Biologie, Médecine, Santé']
- HAL Identifier
- 4329446
- Institution
- ['Centre Hospitalier Régional Universitaire de Nancy', 'Institut National de la Santé et de la Recherche Médicale', 'Université de Lorraine', 'French-Clinical Research Infrastructure Network - F-CRIN [Paris]', 'Institut Lorrain du Coeur et des Vaisseaux Louis Mathieu [Nancy]', 'REICATRA, Recherche et Enseignement en IC Avancée, Transplantation, Assistance', 'Direction Régionale du Service Médical (DRSM) Grand Est, Strasbourg, France', 'Karolinska Institutet [Stockholm]', 'Direction de la Coordination de la Gestion du Risque (DCGDR) Grand Est', 'Caisse Nationale d’Assurance Maladie', 'Université de Lorraine, APEMAC']
- Laboratory
- ['Défaillance Cardiovasculaire Aiguë et Chronique', "Centre d'investigation clinique plurithématique Pierre Drouin [Nancy]", 'Cardiovascular and Renal Clinical Trialists [Vandoeuvre-les-Nancy]']
- Published in
- France
Table of Contents
- Risk of readmission and death after hospitalization for worsening heart failure Role of post-discharge follow-up visits in a real-world study from the Grand Est Region of France 1
- Abstract 249 words 3
- Background and Aims 3
- Methods 3
- Results 3
- Conclusion 3
- Keywords 3
- Introduction 4
- Materials and methods 4
- Population and study design 4
- Outcomes 5
- Groups based on post-discharge follow-up 5
- Definition of covariates 5
- Statistical analysis 5
- Ethical statement 6
- Results 7
- Patients characteristics and post-discharge follow-up 7
- Association of GP cardiologist or combined follow-up with hospital readmission 7
- Association between combined follow-up and outcomes according to age category 8
- Sensitivity analysis after the exclusion of patients who died within 2 months. 8
- Sensitivity analysis by income level according to access to complementary universal 8
- Sensitivity analysis using propensity score to account for baseline differences 8
- Discussion 9
- Epidemiology and determinants associated with healthcare follow-up 9
- Effect of combined follow-up on mortality 10
- Effect of combined follow-up on hospitalization 10
- Impact in clinical practice 11
- Limitations 11
- Conclusion 12
- Acknowledgments 12
- Funding statement 12
- Conflict of interest 13
- Data availability statement 13
- References 14
- Tables 21
- Table 1 Baseline characteristics of the study population 21
- Table 2 Initial occurrence of events of interest after discharge 22
- Table 3 Multivariate analysis of parameters associated with post-discharge follow-up 24
- Table 4 Association of GP Cardiologist and combined follow-up with one-year and long-term outcome in Cox regression 25
- Table 5 Association of GP Cardiologist and combined follow-up with one-year and long-term outcome in Cox regression after 26
- Figures 27
- Figure 1 Event curves for one-year mortality A and one-year heart failure rehospitalization B according to follow-up FU 27
- Figure 2 Association between combined follow-up and mortality A and rehospitalization B at one-year according to age 29
- 044 29
- 069 073 29
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- 55 55-64 65-74 75-84 85 29
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- 55 55-64 65-74 75-84 85 30
- Graphical Abstract 31
- Supplementary material 32
- Supplementary Table 1 Multivariate analysis of parameters associated with post-discharge follow-up excluding patients who died 32
- Supplementary Table 2 Association between combined follow-up and outcomes according to age category 33
- Supplementary Table 3 Association of GP Cardiologist and combined follow-up with one-year and long-term outcome in Cox 33
- Supplementary Table 4 Association of GP cardiologist and combined follow-up with one-year and long-term outcome in Cox 34
- Supplementary Table 5 Interaction between complementary universal medical coverage status and combined FU dependent-time 34
- Supplementary Table 6 Baseline characteristics according to follow-up before and after inverse probability weighting 35
- Supplementary Figure 1 Event curves for mortality A and heart failure rehospitalization B according to follow-up FU 36