EMBARGOED UNTIL 12:01 A.M. WEDNESDAY, APRIL 28, 2021

WEDNESDAY, APRIL 28, 2021 Contact: The North American Menopause Society Eileen Petridis (epetridis@wearefalls.com) Phone: (216) 696-0229 Can Genetics Predict Bothersome Hot Flashes? New study suggests that some of the same genetic variants that help to predict reproductive aging are associated with frequency and severity of hot flashes CLEVELAND, Ohio (April 28, 2021)—Hot flashes are a hallmark of. [...] In this study involving more than 1,200 women of various ethnicities, researchers concluded that some of the same genetic factors that predict reproductive aging may also be associated with hot flashes, thus suggesting that genetics may play a role in predicting the severity and frequency of a woman’s hot flashes. [...] Factors shown to affect reproductive aging and likely to influence a woman’s experience with hot flashes include the age at menarche and the age at menopause. [...] Results are published in the article “Genetic variants predictive of reproductive aging are associated with vasomotor symptoms in a multiracial/ethnic cohort.” “This study found that genetic factors associated with aging of the reproductive system may be linked to vasomotor symptoms during the menopause transition and differ across racial/ethnic groups. [...] Founded in 1989, The North American Menopause Society (NAMS) is North America’s leading nonprofit organization dedicated to promoting the health and quality of life of all women during midlife and beyond through an understanding of menopause and healthy aging.