The twin pillars of Disease Models & Mechanisms

This globally shared experience has brought home how important basic and translational science is for probing disease aetiology and advancing diagnosis and therapy, and how imperative it is that the results of scientific research are freely accessible to anyone and everyone. [...] research and accessibility – are the twin cells, organoids, tissue explants and organotypic cultures, as well as pillars of Disease Models & Mechanisms advanced bioengineering and in vitro models, such as human organ-chips and bioprinted models. [...] large datasets from patients and model systems provides a wealth of We will also increase the number of Review and Opinion articles, information with which to gauge alignment between models and commissioned from clinical and non-clinical colleagues, and human disease, and to test new hypotheses. [...] The distinguished and practising Moving beyond snapshots of static disease states, we aim to report scientists who run the company ensure that its activities are on models that capture the patient journey through disease and responsive to the community. [...] This is an area where sophisticated models might reveal fellowships, and funding and running DMM Workshops and novel drug targets and help us to better understand how the body Journal Meetings (Justice et al., 2020; Nicholson and Hmeljak, responds to disease resolution and therapy.