cover image: Catalyzing CommerCializ ation - Biopreservation material Could end the Wait for organ transplants

20.500.12592/f58dhv

Catalyzing CommerCializ ation - Biopreservation material Could end the Wait for organ transplants

20 Apr 2021

Only metabolism and prevent injury to protein-like function into a synthetic 10% of the worldwide need for organ the organ. [...] Among the large solid organs, the temperature further would help extend and other teams, X-Therma demon- lungs, intestine, and heart have the the life of the organ, a temperature less strated in a preclinical animal model lowest utilization, partially due to their than 0°C allows ice crystals to form, that a heart can be brought back to life very short preservation times. [...] technology to address the critical focused on rolling out a Current Good However, development in the past challenges of organ transport. [...] The Manufacturing Practice (cGMP)-grade four decades has seriously lagged in company’s first-in-the-field technology cell preservation product in 2021 for innovations to extend the timeframe of was inspired by antifreeze proteins clinical use in cell therapy. [...] in arctic fish that effectively bind therapy, X-Therma products provide a During transport, the organ can nucleated ice to control ice growth and huge advantage in the manufacturing suffer ischemic injury due to lack avoid cellular damage.
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