The purpose of the IOMC is to promote co-ordination of the policies and activities pursued by the Participating Organisations, jointly or separately, to achieve the sound management of chemicals in relation to human health and the environment. [...] This document is published under the responsibility of the Joint Meeting of the Chemicals Committee and the Working Party on Chemicals, Pesticides and Biotechnology. [...] From the synthesis process, the substance is obtained in the form of a melt that is transferred in a closed system to a melt granulation tower to yield the test substance shaped as granules. [...] The impact of the diminished health of the fish on the reported BCF is unknown. [...] With the exception of a decrease of the body weight gain and some hematological effects (which could be secondary to an increased diuresis) at very high dose levels, the most common finding observed in these studies is changes of the refractive power of the lens.
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