Human monkeypox: secondary attack rates

Among the 2278persons who had close contact with 24S monkeypox patients infectedfrom an animal source, 93fell ill and were presumed to have been infectedfrom the known human source: 69 of these were spread in the first generation, 19 in the second generation, and the remaining five cases in the third andfourth generation. [...] The local inhabitants wildlife, the mode of virus transmission from wildlife were checked for clinical signs and symptoms of cur- to humans, and the extent of person-to-person trans- rent or recent vesiculo-pustular disease and for the mission. [...] Their age distribution (Table 1) matched contacts, but whose onset of illness occurred within the age distribution of the general population; 2657 of the first week after onset of rash in the primary case, them (72%) had a vaccination scar and the rest were is regarded as a co-primary case, attributable to the regarded as unvaccinated. [...] The distribution of Secondary attack rates primary and co-primary cases, as well as presumed As there were 69 secondary cases (first generation secondary cases, by their generation rank and year of only), the observed crude secondary attack rate occurrence during the six-year period of observation among contacts of the primary and co-primary cases is shown in Table 3. was 0.03 (69/2278); that is, [...] The overall risk of attack for contacts 1420 (62%) of these contacts lived in the same house- living in the same residence as the monkeypox case Table 4. Secondary attack rates amnong close contacts of primary and co-primary cases, according to the contacts' vaccination status' and place of residence Unvaccinated contacts Vaccinated contacts No.