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An increase in the illicit trafficking of raw material instead of refined drugs and the associated relocation of drug laboratories closer to the destination countries with the goal to minimize the loss in case of an interception of the shipment, were noted. [...] From the start of criminal proceedings related to drug trafficking, the confiscation of the proceeds and instrumentalities of the crime, along with the conviction of the perpetrators, should be an integral objective of the case strategy. [...] The three international drug control conventions were adopted to protect the health and welfare of humankind, with the intention to make essential medications available for the relief of pain and the alleviation of suffering, while protecting the people, particularly the most vulnerable, from the potentially dangerous effects of controlled substances. [...] The implementation of the provisions of the drug control conventions and the policy commitments adopted by the Commission since 2009 are crucial to further the attainment of the 2030 Agenda on Sustainable Development. [...] During the 2020 CND thematic discussions, participants highlighted a range of measures to address the low to non-existence of the availability of internationally controlled substances for medical and scientific purposes, including for the relieve of pain and palliative care, in many parts of the world, including79: • Ensure the availability of controlled substances drugs for medical and scientific.