TECHNICAL REPORT - Evidence for the effectiveness of interventions to prevent infections among

The aim of the work was to assess the latest evidence on the effectiveness of select interventions — specifically, drug treatment, needle and syringe programmes (NSPs), drug consumption rooms and the combination of opioid agonist treatment (OAT) and NSPs — in the prevention of hepatitis C virus (HCV) transmission, HIV transmission, injecting risk behaviour (IRB) and injection frequency (IF) among. [...] Conclusions and recommendations for future research There is now a strong body of empirical evidence for the effectiveness of OAT and NSPs and for the combination of these two interventions in preventing HCV and HIV transmission and IRB. [...] In order to update the guidance, five packages of work were undertaken: • an update of the review of reviews (RoR) on the effectiveness of NSPs (existing intervention), drug treatments (existing intervention) and drug consumption rooms (DCRs) (new intervention), • a literature review of modelling studies of the population-level impacts of drug treatments and NSPs (new component), • a systematic re. [...] It may provide statements on the an accurate summary of the results of the effectiveness of available studies included in the review interventions Low One critical flaw with or without non-critical Included as a weaknesses: the review has a critical flaw and ‘supplementary review’ to may not provide an accurate and derive evidence-based comprehensive summary of the available statements on the stud. [...] To be consistent with the 2011 RoR — the evidence reviews undertaken to inform the 2011 guidance and described in the technical reports (ECDC, 2011a, 2011b) — the same approach to assessing primary study quality was applied: a systematic critical appraisal of the primary studies was not undertaken; rather, the study design was used as an indication of the inferences that could be drawn from the st.