Nature (covering the water, biodiversity, soil/land, and air/climate realms) continues to decline with significant negative impacts on society. Businesses need to understand their impacts and dependencies on nature, manage their nature-related risks and embed the value of nature into their decision making to identify and implement opportunities that contribute towards the nature-positive global goal. Achieving nature-positive requires collective action across sectors, value chains and landscapes. Fundamentally, nature-positive represents a systemic and transformative shift rather than ‘re-shaping’ of current practices. Utilising prioritisation approaches can enable businesses to identify areas where they can have a material and meaningful contribution from the outset as systemic and transformative change is adopted through the business.