TECHNICAL REPORT - Evidence for the effectiveness of interventions to prevent infections among

Each of the included studies was graded based on the model type used in the study and on the quality of the parameterisation of the model with regards to the data sources used to obtain estimates for the efficacy of interventions. [...] This process examined the type of model used in the study and assessed the quality of the parameterisation of the model with regards to the data sources used to obtain estimates for the efficacy of interventions. [...] 40 11 FIGURE 1 Illustrative example of the ‘relative reduction in incidence/prevalence at the end of the study period between the baseline and comparison scenarios The key explanatory variables in the analysis are measures of the change in coverage of OAT and NSPs and the increase in DAA treatments. [...] Note that there is a strong association with an increase in DAA coverage, as indicated by the colour coding (10) Note that the value of the regression coefficient for DAA treatment should not be compared with the value of the regression coefficient for the reduction in the coverage gap for OAT and NSPs because the treatment measure is not a percentage, unlike the OAT and NSP measures. [...] Data points were considered ineligible for inclusion in the linear regression analysis if the incidence/prevalence reduction over the study period in the baseline scenario exceeded 99 %, the incidence was less than 0.1 per 100 person-years at the end of the study period or the prevalence was less than 0.1 % at the end of the study period.